TY - JOUR T1 - Airway inflammation and inhaled corticosteroids in COPD JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.00289-2017 VL - 49 IS - 6 SP - 1700289 AU - Sukhwinder Singh Sohal AU - Mathew Suji Eapen AU - Chris Ward AU - Eugene Haydn Walters Y1 - 2017/06/01 UR - http://erj.ersjournals.com/content/49/6/1700289.abstract N2 - We read with interest the recent article by Kunz et al. [1] in the European Respiratory Journal (ERJ), and the appropriately questioning accompanying editorial by Calverley [2] in the same issue, considering airway inflammation and effects of inhaled corticosteroids (ICS) in chronic obstructive pulmonary disease (COPD). Understanding COPD pathology is a hugely important area and it is encouraging that leading respiratory journals are recognising this. We would like to suggest that a broader discussion of new insights into COPD pathology might have been appropriate. Thus, a more integrated consideration of overall airway wall cellularity, vascularity, epithelial–mesenchymal transition (EMT) and the effects of ICS on these in COPD is urgently needed to aid discussion of this devastating pathophysiology.There is a need for in-depth discussion of new insights in COPD airway pathogenesis http://ow.ly/RDFM30bxduu ER -