TY - JOUR T1 - Community acquired pneumonia and co-existing acute kidney injury have poor clinical outcomes JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2016.PA2587 VL - 48 IS - suppl 60 SP - PA2587 AU - Sarah Paterson AU - Alexandra Bramley AU - Jennifer Thornley AU - Rajesh Yadavilli Y1 - 2016/09/01 UR - http://erj.ersjournals.com/content/48/suppl_60/PA2587.abstract N2 - Background: Severity of acute kidney injury and community acquired pneumonia are individually poor prognostic factors. This study will investigate the outcomes of patients presenting with both.Aim: To assess the effect of stage of acute kidney injury (AKI) on overall prognostic outcomes in patients with community acquired pneumonia (CAP).Method: Data was collected retrospectively from a cohort of patients presenting with acute pneumonia in a district general hospital between October and December 2015. CURB-65 and AKI Rifle scores were applied respectively. Patient demographics, length of hospital stay (LOS) and 30 day mortality were recorded.Results: 39 patients with CAP and AKI were studied. The average age was 79.9 years, the overall 30 day mortality rate was 38% (n=15) and mean LOS for surviving patients was 10.5 days (n=24).Table 1 summarises data for CURB-65 scoring, AKI staging, length of hospital stay and 30 day mortality rate.CAP GroupAKI StageNo of patientsAverage age (yrs)Average LOS (days)30 day mortality %CURB-65: 11375.34020---30---CURB-65: 21975.69.511.12585.212.754030---CURB-65: 311481.611.1457.125771240319115-CURB-65: 41282.52100Data for CURB-65 scoring, AKI staging, LOS and 30 day mortalityConclusions: There is correlation between severity of CAP and presence of AKI. Patients admitted with a greater severity of CAP are more likely to have concurrent AKI on presentation and are more likely to die from the combination.CAP associated with AKI presents a higher risk of mortality and increased LOS, thus early recognition and optimal management of both should be emphasised in order to improve clinical outcomes. ER -