RT Journal Article SR Electronic T1 Prevalence of ocular sarcoidosis in patients with intra thoracic sarcoidosis JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA3730 DO 10.1183/13993003.congress-2016.PA3730 VO 48 IS suppl 60 A1 Muhammad Hussain A1 Hazim Mahdi A1 Mohammed Hassan YR 2016 UL http://erj.ersjournals.com/content/48/suppl_60/PA3730.abstract AB Introduction: Sarcoidosis is an inflammatory multi system granulomatous disease of unknown etiology. Diagnosis of sarcoid is established on the basis of compatible history, clinical & radiological findings, supported by histological evidence of non caseating granuloma. The eye & adnexa are involved in 25-80% of patients with sarcoidosis. Literature review does indicate that conjuntival biopsy carries low morbidity with high positive yield.Material & Method: Proforma designed. All diagnosed sarcoid patients were subjected to detail ophthalmology history & examination.Results: 52 cases were registered during study period. 47 included as 5 had incomplete information as per proforma.Age & Sex;: 24(51%) had eye symptoms 35(74%) consented for eye examination. 13(37%) of them had abnormal finding on ocular examination. AGENumberMaleFemale21- 401613341-60251213Above 60615AGE & GenderSymptomsNumberDry Eye8Blurring of Vision6Red Eye2Pain & Red5Dry & Red3Eye SymptomsDiscussion: 76.6.% had histological diagnosis. 23 out of 36 had bronchoscopy/EBUS..Study revealed fairly high prevalence of ocular symptoms amongest sarcoid patients (51%) & 37% of them had abnormal eye examination finding. Non of our patient had conjunctival biopsy. literature review indicate that conjunctival biopsy is positive in up to 66% of cases with conjunctival follicles & up to 31% without it. conjunctival biopsy in presence of pulmonary infiltrate is reported to be positive in 51.6% patients.Considering our study finding we may conclude that requesting conjuntival biopsy will reduced our need of transbronchial /EBUS need. This will be cost effective & more convenient for the patients.