TY - JOUR T1 - COPD-6 mini-spirometer: Feasible for early detection of COPD in general practice? JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2016.PA3931 VL - 48 IS - suppl 60 SP - PA3931 AU - Peter Kjeldgaard AU - Jesper Lykkegaard AU - Heidi Spillemose AU - Charlotte Suppli Ulrik Y1 - 2016/09/01 UR - http://erj.ersjournals.com/content/48/suppl_60/PA3931.abstract N2 - Background and Aim: Opportunistic screening for COPD in General Practice (GP) is possible, but barriers exist, especially the large number of spirometries calls for facilitated procedures. Mini-spirometers (measuring FEV1 and FEV6) may offer a quick tool to select subjects for conventional spirometry. Our aim was to investigate, if pre-screening with a COPD-6 mini-spirometer can facilitate early detection of COPD in a primary care setting.Methods: In a primary care setting, subjects at high risk of COPD, (i.e. age ≥35, exposure, and at least one respiratory symptom) were screened for airway obstruction (FEV1/FEV6 <0.7) with a COPD-6 mini-spirometer. Subjects with either airway obstruction or FEV1 <80%pred, had a confirmative spirometry and tested for bronchodilator (BD) reversibility; and based on the findings classified as COPD (post-BD FEV1/FVC <0.7), asthma (post-BD FEV1 change ≥0.50 L) or other.Results: A total of 2990 subjects (54% males) were enrolled (mean age 59 years and 28 pack-years); and 949 (32%) of the subjects proceeded to diagnostic spirometry. The criteria for proceeding to diagnostic spirometry were: 54% FEV1/FEV6 <0.7, 40% FEV1 <80%pred and 6% MDs decision. Of these subjects, the diagnoses were as follow: 51% COPD, 3% asthma and 42% other. Overall, a diagnosis of COPD was made in 487 (16%) of the population; of these subjects 72% and 23%, respectively, had conventional spirometry based on low FEV1/FEV6 ratio and FEV1 ≤80%pred.Conclusion: Pre-screening with the COPD-6 device showed acceptable specificity for selection of subjects for diagnostic spirometry and is likely to be a useful alternative to current practice in primary care. ER -