TY - JOUR T1 - Tidal volumes and ETCO<sub>2</sub> levels during resuscitation and prematurely born infants' outcomes JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2016.PA1290 VL - 48 IS - suppl 60 SP - PA1290 AU - Anoop Pahuja AU - Vadivelam Murthy AU - Prashanth Bhat AU - Anthony Milner AU - Anne Greenough Y1 - 2016/09/01 UR - http://erj.ersjournals.com/content/48/suppl_60/PA1290.abstract N2 - Background: Intraventricular haemorrhage (IVH) and bronchopulmonary dysplasia (BPD) are major complications of very premature birth. Respiratory function monitoring has shown expired tidal volumes (VTe) and end tidal carbon dioxide (ETCO2) levels are very variable during the resuscitation.Aims and objectives: To test the hypothesis that prematurely born infants who developed an IVH or BPD had high VTe (&gt;6mls/kg) and/or low ETCO2 levels during resuscitation and stabilisation in the labour suite.Methods: Infants with a gestational age&lt;34 weeks requiring resuscitation at birth were assessed; VTes and ETCO2 levels were simultaneously recorded using a respiratory function monitor.Results: 80 infants had respiratory monitoring: 36 developed an IVH and 34 BPD. VTe and ETCO2 levels from 34,8208 inflations were assessed. Those who developed an IVH compared to those who had no IVH had a greater number of inflations with a high VTe (p 0.001) and a low ETCO2 (p 0.01). Minute ventilation (p 0.001) and respiratory rate (p 0.001) were greater in the IVH group. All results were significant after correcting for differences in gestational age and birth weight between groups. The IVH group had higher arterial CO2 levels (median of 6.2 (3-10) vs 5.3 (4.3-8) kPa (p 0.01)) on NICU arrival. There were similar trends in “BPD” infants, but the differences were of lower significance (p&lt;0.05). There were no significant differences in the duration of resuscitation between infants who developed an IVH or BPD or neither complication.Conclusions: Routine respiratory function monitoring the labour suite might reduce variability in resuscitation and improve outcomes of prematurely born infants. ER -