TY - JOUR T1 - Cholesterol granuloma of the anterior mediastinum with osseous metaplasia JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2016.PA2521 VL - 48 IS - suppl 60 SP - PA2521 AU - Premjithlal Bhaskaran AU - Maria Montero Fernandez AU - Georgia Hardavella AU - Jaymin Morjaria AU - Nikolaos Anastasiou Y1 - 2016/09/01 UR - http://erj.ersjournals.com/content/48/suppl_60/PA2521.abstract N2 - Cholesterol granuloma is a well-characterized entity comprised of a foreign-body giant cell-reaction that forms in response to the presence of cholesterol crystals1. It is usually found in the middle-ear or mastoid process in patients with diseases associated with chronic inflammation such as cholesteatoma and otis media. They are rarely seen in the mediastinum. In fact osseous metaplasia is an exceedingly rare feature of cholesterol granulomas only reported three times inliterature. Here we report a case of a 67 year old woman who was referred to us for evaluation of a incidental mediastinal mass that was identified while investigating the aetiology of anaemia, which was resected. Histological identification revealed a cholesterol granuloma. She had an uneventful recovery and was discharged from any further follow-up. This case identifies an incidental cholesterol granuloma of the anterior mediastinum with osseous metaplasia, a rare finding. Anterior mediastinal masses can have a sinister aetiology and present with or without clinical symptoms. It is prudent to investigate them and if appropriate resection is the treatment of choice. ER -