RT Journal Article SR Electronic T1 Diagnostic accuracy of pleural fluid adenosine deaminase in patients with tuberculous pleural effusion while keeping pleural biopsy as a gold standard JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA2769 DO 10.1183/13993003.congress-2016.PA2769 VO 48 IS suppl 60 A1 Nausheen Saifullah A1 Saifullah Baig A1 Jagdesh Kumar A1 Nadeem Rizvi YR 2016 UL http://erj.ersjournals.com/content/48/suppl_60/PA2769.abstract AB OBJECTIVES: To determine the diagnostic accuracy of pleural fluid adenosine deaminase in patients with tuberculous pleural effusion while keeping pleural biopsy as a gold standard.STUDY DESIGN: Descriptive Cross-sectional study.SUBJECTS AND METHODS: 114 patients who fulfilled the inclusion criteria were included in the study. Pleural tap was done and 20 ml of pleural fluid was sent to laboratory for ADA level and at the same time Abram's pleural biopsy was done from the same site.RESULTS: Mean age of the patients was 40.28±16.31 years. Gender distribution showed 62 patients (54.4%) were male while 52 patients (45.6%) were female. Pleural fluid adenosine deaminase (ADA) showed sensitivity (86.36%), specificity (61.54%), diagnostic accuracy (80.70%), positive predictive value (88.37%) and negative predictive value (82.42%) confirmed by pleural biopsy as a gold standard.CONCLUSION: It is concluded from this study that although Biopsy is the gold standard in diagnosing tuberculosis pleural effusion. ADA is cheap, readily available and non-invasive test that shows good diagnostic accuracy in tuberculosis pleural effusion.