PT  - JOURNAL ARTICLE
AU  - Nausheen Saifullah
AU  - Saifullah Baig
AU  - Jagdesh Kumar
AU  - Nadeem Rizvi
TI  - Diagnostic accuracy of pleural fluid adenosine deaminase in patients with tuberculous pleural effusion while keeping pleural biopsy as a gold standard
AID  - 10.1183/13993003.congress-2016.PA2769
DP  - 2016 Sep 01
TA  - European Respiratory Journal
PG  - PA2769
VI  - 48
IP  - suppl 60
4099  - http://erj.ersjournals.com/content/48/suppl_60/PA2769.short
4100  - http://erj.ersjournals.com/content/48/suppl_60/PA2769.full
SO  - Eur Respir J2016 Sep 01; 48
AB  - OBJECTIVES: To determine the diagnostic accuracy of pleural fluid adenosine deaminase in patients with tuberculous pleural effusion while keeping pleural biopsy as a gold standard.STUDY DESIGN: Descriptive Cross-sectional study.SUBJECTS AND METHODS: 114 patients who fulfilled the inclusion criteria were included in the study. Pleural tap was done and 20 ml of pleural fluid was sent to laboratory for ADA level and at the same time Abram's pleural biopsy was done from the same site.RESULTS: Mean age of the patients was 40.28±16.31 years. Gender distribution showed 62 patients (54.4%) were male while 52 patients (45.6%) were female. Pleural fluid adenosine deaminase (ADA) showed sensitivity (86.36%), specificity (61.54%), diagnostic accuracy (80.70%), positive predictive value (88.37%) and negative predictive value (82.42%) confirmed by pleural biopsy as a gold standard.CONCLUSION: It is concluded from this study that although Biopsy is the gold standard in diagnosing tuberculosis pleural effusion. ADA is cheap, readily available and non-invasive test that shows good diagnostic accuracy in tuberculosis pleural effusion.