PT  - JOURNAL ARTICLE
AU  - Jihène Ayachi
AU  - Ahmed Khedher
AU  - Rahma Ben Jazia
AU  - Meddeb Khaoula
AU  - Aissa Sana
AU  - Ben Salem Halima
AU  - Gargouri Imen
AU  - Benzarti Mohamed
AU  - Boussarsar Mohamed
AU  - Ahmed Abdelghani
TI  - Outcome and prevalence of sleep breathing disorders (SBD) after an acute exacerbation of obesity-hypoventilation syndrome AE/OHS
AID  - 10.1183/13993003.congress-2016.PA2133
DP  - 2016 Sep 01
TA  - European Respiratory Journal
PG  - PA2133
VI  - 48
IP  - suppl 60
4099  - http://erj.ersjournals.com/content/48/suppl_60/PA2133.short
4100  - http://erj.ersjournals.com/content/48/suppl_60/PA2133.full
SO  - Eur Respir J2016 Sep 01; 48
AB  - Background: The incidence of obesity hypoventilation syndrome (OHS) may be increasing. Despite polysomnographics parameters and extensive NIV use in these patients, information about efficacy is limited.Aims and objectives: Evaluate the prevalence and typology of SBD in severe OHS patients.Evaluate compliance and side effects of at home NIV in these patients.Methods: Were included all consecutive patients admitted to ICU within 13 Years. Anthropometric, clinical, functional,ABGs data were collected and Epworth scale was measured. Respiratory polygraphy was performed at steady state. Compliance and observance to NIV were analyzed.Statistical analysis was performed for prevalence of SDB and NIV compliance was also analyzed.Results: We included 100 patients.50% of patients required immediate invasive mechanical ventilation. NIV was only possible in 44%. Overall ICU mortality was 39%. The patients are mostly old, female with morbid obesity. 61 patients improved and were directed to the respiratory department. Six patients died within a delay of 16,1±16,2months from ICU discharge. Only 24 patients were be reached for a respiratory polygraphy. All patients have an abnormal Epworth scale. The AHI average is 48±29/h and time spent with SpO2<90% at 144.0±171,8min. 70.8% of patients had obstructive sleep apnea syndrome. Ventilatory treatment at home by NIV has been prescribed in 21.3% of cases with good compliance only in 36.4% of cases. The average compliance of home NIV was 7 ±3.5 hrs per day.Conclusion: This comprehensive study demonstrated a poor outcome of AE/OHS. We noted a high prevalence of OSA. Most of these patients are lost to follow.