PT  - JOURNAL ARTICLE
AU  - Zoran Arsovski
AU  - Biserka Kjaeva
AU  - Dejan Dokic
AU  - Zlatica Goseva
AU  - Sava Pejkovska
AU  - Elena Janeva
AU  - Suzana Arbutina
AU  - Angela Debreslioska
AU  - Anita Arsovska
TI  - Positive microbiology findings in non-cystic fibrosis bronchiectasis and co-morbidities
AID  - 10.1183/13993003.congress-2016.PA2558
DP  - 2016 Sep 01
TA  - European Respiratory Journal
PG  - PA2558
VI  - 48
IP  - suppl 60
4099  - http://erj.ersjournals.com/content/48/suppl_60/PA2558.short
4100  - http://erj.ersjournals.com/content/48/suppl_60/PA2558.full
SO  - Eur Respir J2016 Sep 01; 48
AB  - Background: Bronchiectasis are becoming a focus of the respiratory scientists in recent years.Aim of the study: To assess microbiology findings in non-cystic fibrosis bronchiectasis (non-CFB) and frequency of associated co-morbidities.Material and methods: We analyzed 172 patients with non-CFB as a primary diagnosis that were hospitalized during a period of 61 months.Results: Positive microbiology analysis was obtained in 26,74% of the patients. 14,53% of the patients had positive results on Candida albicans. The most frequent pathogen found in sputum was Pseudomonas aeruginosa (5,81%). In 3,48% Acinetobacter species was found and E. Coli and Haemophyllus influenzae were both found in 1,74 % of the patients. Other findings were Streptococcus pyogenes, Streptococcus pneumoniae, Enterobacter aerogenes, Klebsiela pneumoniae, Aspergillus niger, Aspergillus fumigatus, Stenotrophomonas maltophilia etc. In 5,23% of patients coexistence of Candida albicans with other bacterial pathogens was found. 56,66% of the non-CFB patients with positive pathogen findings had chronic respiratory insufficiency. COPD coexisted with non-CFB in 26,66% of the patients with positive pathogen microbiology findings. Co-existence of non-CFB with other co-morbid conditions were found (i.e Kartagener Syndrome, Wegener's granulomatosis, Alcoholism, Myelodysplastic Syndrome, Esophagotracheal fistula etc). Appropriate drug treatment was carried out in all patients and one patient with esophagotracheal fistula was transferred to Surgery for consecutive treatment.Conclusion: Mayor part of fungal findings represent only colonization. Management of non-CFB should consider other co-existingdiseases and patient's condition.