RT Journal Article
SR Electronic
T1 Microbiological spectrum and susceptibility pattern of clinical isolates from the Respiratory Intensive and Post-Intensive Care Unit of University Hospital Center Zagreb, Croatia
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP PA2629
DO 10.1183/13993003.congress-2016.PA2629
VO 48
IS suppl 60
A1 Gordana Pavlisa
A1 Andrea Vukic Dugac
A1 Ana Hecimovic
A1 Hrvoje Puretic
A1 Marko Jakopovic
A1 Miroslav Samarzija
YR 2016
UL http://erj.ersjournals.com/content/48/suppl_60/PA2629.abstract
AB Background: Respiratory tract infections are the frequent infections among patients hospitalized in respiratory units. The increased drug resistance has become an important clinical problem.Aims and objectives: To evaluate the incidence of multiresistant bacterial pathogens in patients treating in the respiratory intensive and post-intensive care unit of University Hospital Center Zagreb, Croatia.Methods: Between January 2013 and December 2014, patients admitted to the respiratory intensive and post-intensive care unit were enrolled in the study. Respiratory specimens (sputum or bronchoalveolar lavage) were analyzed for all the patients. All bacteria were identified by standard microbiologic methods, and their antibiotic susceptibility testing was performed using disk diffusion method.Results: The frequencies of Gram-positive and Gram-negative multiresistant bacteria were 7.6% and 92.4%, respectively. Staphylococcus aureus (MRSA) was the most common multiresistant isolate among the Gram-positive organisms, while Pseudomonas aeruginosa, Klebsiella pneumoniae and Acinetobacter baumannii were the 3 leading Gram-negative isolates. Staphylococcus aureus (MRSA) was isolated in 0.56% of patients, Pseudomonas aeruginosa in 2.45%, Klebsiella pneumoniae 1.84%, while Acinetobacter baumannii in 0.87% of patients.Conclusions: Gram-negative multiresistant bacteria (P. aeruginosa, ESBL-producing K. pneumoniae and Acinetobacter baumannii) were the most important pathogens. Early bacteriological diagnosis and susceptible testing is required for successful treating of those patients.