RT Journal Article SR Electronic T1 Comparison of functionality and symptoms in COPD patients with different nutritional status JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA4449 DO 10.1183/13993003.congress-2016.PA4449 VO 48 IS suppl 60 A1 Torres Sanchez, Irene A1 Valenza, Marie Carmen A1 Del Corral Núñez-Flores, Tamara A1 López-López, Laura A1 Rodríguez-Torres, Janet YR 2016 UL http://erj.ersjournals.com/content/48/suppl_60/PA4449.abstract AB Introduction: Nutritional disturbances in patients with chronic obstructive pulmonary disease (COPD) are common. Different studies have related the severity of the disease with nutrition.Objectives: To evaluate the nutritional status in COPD patients, and to compare the functionality and symptoms in COPD patients with different nutritional statusMethods: Observational study. Nutritional status was evaluated with the Mini Nutritional Assessment and patients were grouped depending on their punctuation. Clinical profile was evaluated including respiratory function, independence levels, quality of life and anxiety and depression. Additionally, functionality related to symptoms and respiratory symptoms were evaluated.Results: 154 patients were included, 98 of them were males. 71 patients showed malnutrition and 83 had a normal nutritional status.VariableMNA ≥ 24 (n=83)MNA < 24 (n=71)p-valueClinical profileFEV1%35.71±14.4335.18±20.100.859HAD total score12.82±7.3716.27±8.210.007*Barthel Index94.40±8.5085.51±20.170.001*SGRQ total score59.89±13.9268.10±11,21p<0.001**Functionality related to symptomsLCADL total score27.17±12.2633.52±15.820.031*SymptomatologyDyspnea5.36±2.546.19±2.530.043*LCQ total score15.01±3.2613.37±3.920.070FEV1: Forced expiratory volume in the first second; HAD: Hospital anxiety and depression scale; SGRQ: Saint George Respiratory Questionnaire; LCADL: London Chest Activity of Daily Living Scale; LCQ: Leicester Cough Questionnaire; p<0.05*; p<0.001**TABLE 1. Comparison of COPD with different nutritional statusConclusion: Patients with COPD and malnutrition have worse results in functionality and symptomatology than patients with COPD without malnutrition.