TY - JOUR T1 - LATE-BREAKING ABSTRACT: Randomised controlled trial of telemonitoring with addition of daily forced oscillation in older people with COPD and co-morbidity JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2016.OA3519 VL - 48 IS - suppl 60 SP - OA3519 AU - Pasquale Pompilio AU - Paolo Zanaboni AU - Trine Bergmo AU - Tanja Grzetic Romcevic AU - Valentina Isetta AU - Christer Janson AU - Andrei Malinovschi AU - Dorijan Marusic AU - Jo Middlemass AU - Josep Montserrat AU - Giulia Munaro AU - Kaiu Prikk AU - Ruth Sepper AU - A. Niroshan Siriwardena AU - Peter Calverley AU - Raffaele Dellaca AU - Roberto Rosso AU - Paul Walker Y1 - 2016/09/01 UR - http://erj.ersjournals.com/content/48/suppl_60/OA3519.abstract N2 - Evidence of clinical benefit and cost-effectiveness from daily symptom and simple telemonitoring in COPD is unproven. The CHROMED study explored the effect of telemonitoring in older people with COPD and significant co-morbidity who performed daily forced oscillation measurements via RESMON PRO DIARY to identify early physiological change associated with an exacerbationSix centres in 5 countries randomised 312 people to 9 months telemonitoring (154) or daily symptom questionnaires (158). Each day the monitored group recorded symptoms, pulse, BP, oxygen saturation and airway resistance and reactance. An alert was generated if results exceeded pre-determined parameters and the participant was contacted by their local clinical centre to consider additional treatmentBaseline characteristics were evenly matched: mean age 71 years, FEV1 1.3L (50% predicted) and SGRQ score 49. 61% of subjects had 2+ exacerbations and 42% had been hospitalised in the previous yearTime to first hospitalisation did not differ albeit the monitoring group had fewer hospitalisations (79 vs 103; p=ns) and days in hospital (329 vs. 650; p=ns). However, subjects hospitalized with an AE COPD in the previous year (n=128) had a lower hospitalisation rate (p<0.04). Quality of life (EQ-5D) and health status (CAT) did not differ between groups. Mean cost in the monitored group was marginally lower (€4,615 vs €4,831; p=ns)Telemonitoring including daily forced oscillation impacted neither time to first hospitalisation nor health status. Reduction in hospitalisation rate in subjects with previous hospitalisation suggests these individuals may benefit from telemonitoring and earlier treatment. ER -