PT - JOURNAL ARTICLE AU - Kontorovich Mikhail AU - Syskov Konstantin TI - Application of one-lung high frequency jet ventilation in lung surgery AID - 10.1183/13993003.congress-2016.PA2513 DP - 2016 Sep 01 TA - European Respiratory Journal PG - PA2513 VI - 48 IP - suppl 60 4099 - http://erj.ersjournals.com/content/48/suppl_60/PA2513.short 4100 - http://erj.ersjournals.com/content/48/suppl_60/PA2513.full SO - Eur Respir J2016 Sep 01; 48 AB - INTRODUCTION: In the present day, one-lung jet ventilation is applied in case of a necessity to isolate the healthy lung during operations. HFJV ensures excellent oxygenation of arterial blood, keeps the lungs in a relaxed state without execution of a recruitment maneuver and increases venous return and cardiac output by lowering the workload of the left ventricle.METHODS: Three groups consisting of 50 patients who underwent lung surgery during which two-lungs conventional mechanical ventilation (CMV), one-lung conventional mechanical ventilation (OCMV) and one-lung high frequency jet ventilation (OHFJV) were applied, were compared in terms of gas exchange and hemodynamics parameters. Artificial ventilation was applied through a single-lumen endotracheal tube located in the main bronchus of the healthy lung. In case of necessity of left main bronchus intubation, a correcting triple maneuver was executed. Usage of standard single-lumen endotracheal tubes ensured a good isolation of the healthy lung, facileness of sanitation and bronchoscopic control of the location of the tube.RESULTS: In comparison of OHFJV to OCMV, the results of the study demonstrated a decrease of: PIP by 26.5%; Pes by 81.6%; PVR by 41.7%, an increase of: PaO2 by 66.1%; HBI by 91.0%; CVP by 28.3% and maintaining of normal pH=7.42 and PaCO2=34.5 mm Hg.CONCLUSIONS: Under conditions of OHFJV, even a complete atelectasis of one lung does not go along with a considerable disorder of gas exchange in contrast to OCMV. This enabled a wider application of this kind of ventilation for lung surgeries on patients with distinct gas exchange and hemodynamics disorders.