RT Journal Article SR Electronic T1 Renal impairment a neglected comorbidity in patients with COPD JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA4155 DO 10.1183/13993003.congress-2016.PA4155 VO 48 IS suppl 60 A1 Mohit Bhatia A1 J.K. Samaria A1 Shubham Agarwal A1 Pradeep Nirala YR 2016 UL http://erj.ersjournals.com/content/48/suppl_60/PA4155.abstract AB Aims and objective: Chronic obstructive pulmonary disease associated with various systemic manifestations. Among these cardiovascular diseases are very much talked about, there is very less said about renal impairment in patients with COPD. Renal comorbidity is an important comorbid condition in COPD patients. In our study we tried to find prevalence of renal function impairment in patients with COPD.Material and method: We evaluated 100 cases with COPD1 (post bronchodilator FEV1/FVC< 0.70) both males and females, age ranging between 45 to 75 year (mean age 62). Patients with acute exacerbation and haemodynamicaly instability were excluded from study. All included patients were evaluated for renal function with the help of serum urea, serum creatininne and Glomerular filtration rate estimation using Cockcroft- Gault formula. Now all patients were classified in 4 groups according to GFR (in ml/min/1.73meter2) which correspond to severity of renal impairment. Severe renal impairment (GFR 15-29), moderate (GFR 30-59), mild (GFR 60-89), normal (GFR >90). Obtained data was analysed statistically.Results: In our study we found that 36% patient had raised creatininne levels (>1.2mg/dl) while 48% had a raised urea levels (>40mg/dl). 8% patients had severely reduced GFR, 46 % patients had moderate reduction in GFR and only 30% patients had normal GFR.Conclusion: we conclude that there is high prevalence of renal impairment in patient with COPD. And it is a neglected comorbidity in COPD patients. Its early detection and proper management can reduce morbidity and mortality.reference: 1.GOLD 2016.