PT  - JOURNAL ARTICLE
AU  - Minna Mecklin
AU  - Paula Heikkilä
AU  - Matti Korppi
TI  - Risk factors for intensive care and respiratory support among infants with bronchiolitis
AID  - 10.1183/13993003.congress-2016.PA1595
DP  - 2016 Sep 01
TA  - European Respiratory Journal
PG  - PA1595
VI  - 48
IP  - suppl 60
4099  - http://erj.ersjournals.com/content/48/suppl_60/PA1595.short
4100  - http://erj.ersjournals.com/content/48/suppl_60/PA1595.full
SO  - Eur Respir J2016 Sep 01; 48
AB  - The aim was to evaluate the risk factors for intensive care and for need of respiratory support in infants admitted for bronchiolitis at age less than 12 months.This is a retrospective descriptive case-control study on 80 bronchiolitis (age-specific population 1.4/1000/year) patients treated in pediatric intensive care unit (PICU) and 160 controls treated in the emergency department (ED) or at the ward in Tampere University Hospital, between 2000-2012. A structured form was used to collect medical data of cases and controls separately in the ED, at the ward and in the PICU. Statistically significant risk factors in non-adjusted analyses were included in the adjusted logistic regression.Age < 2 months (adjusted OR 7.0, 95%CI 2.7-18.5), low birth weight (< 2000 g) (adjusted OR 10.7, 95%CI 1.8-64.2), congenital heart disease (adjusted OR 8.5, 95%CI 2.3-31.7), and presence of apneas (adjusted OR 17.9, 95%CI 1.4-223.4) were significant risk factors for the intensive care. Significant risk factors for the need of respiratory support (mechanical ventilation or nasal CPAP) were age < 2 months (adjusted OR 8.5, 95%CI 2.4-30.7), low birth weight (< 2000 g) (adjusted OR 5.8, 95%CI 1.2-28.9) and congenital heart disease (adjusted OR 14.0, 95%CI 3.0-65.6), but not anymore presence of apneas (adjusted OR 2.7, 95%CI 0.4-17.6).Less than 0.25% of infants needed intensive care for bronchiolitis at age less than 12 months. Half (49%) of those treated in the PICU were born prematurely. Low age, low birth weight and congenital heart disease were independently significant risk factors for both intensive care and respiratory support.