PT  - JOURNAL ARTICLE
AU  - Ana Verónica Santos Cardoso
AU  - Nuno Pereira
AU  - Vanessa Santos
AU  - Patrícia Caetano Mota
AU  - Inês Neves
AU  - Natália Melo
AU  - António Morais
AU  - Marta Drummond
TI  - Obstructive sleep apnoea and interstitial lung disease: A quality of life analysis
AID  - 10.1183/13993003.congress-2016.PA2358
DP  - 2016 Sep 01
TA  - European Respiratory Journal
PG  - PA2358
VI  - 48
IP  - suppl 60
4099  - http://erj.ersjournals.com/content/48/suppl_60/PA2358.short
4100  - http://erj.ersjournals.com/content/48/suppl_60/PA2358.full
SO  - Eur Respir J2016 Sep 01; 48
AB  - Purpose: Recent studies report an increased incidence of obstructive sleep apnoea (OSA) among patients with interstitial lung disease (ILD). The actual idiopathic pulmonary fibrosis (IPF) guidelines recognise OSA as an important comorbidity that can affect patient's survival. The aims of our study were to evaluate the prevalence of OSA and its effect on quality of life (QoL) in patients with fibrotic ILD.Methods: Patients with stable fibrotic ILD, excluding those with body mass index (BMI) ³ 30 or significant upper airway pathologies, underwent level III polysomnography, pulmonary function tests, Epworth sleepiness scale (ESS) and multiple QoL tools [Pittsburgh Sleep Quality Index (PSQI); Fatigue Severity Scale (FSS); Short-Form 36 Health Survey (SF-36); Hospital Anxiety and Depression Scale (HADS)].Results: Eleven patients were enrolled (6 male, 5 female; mean age 68.5 ± 13.2 years; mean BMI 25.9 ± 2.9 Kg/m2) with diagnosis of ILD associated with collagen vascular disease (n = 7), IPF (n = 3), and ILD associated with vasculitis (n = 1). The mean predictive percentages of FVC, FEV1 and TLC were in the normal range, DLCO was slightly decreased. The mean ESS was 7.2 ± 6.3 (3 patients with ESS > 10). OSA was diagnosed in 7 (63.3%) patients (5 mild OSA and 2 moderate-to-severe OSA). Only two patients (with IAH ³ 15) initiated CPAP treatment. The assessment of QoL by the PSQI, FSS, SF-36 and HADS, showed a trend towards a worse level in OSA patients.Conclusion: In the present study 63% of patients with fibrotic ILD presented OSA and ESS was not a good screening tool for these patients. A trend to worse QoL was present in patients with this comorbidity.