RT Journal Article SR Electronic T1 Successful wireless monitoring and therapy alteration in home NIV: Proof of principle JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA2897 DO 10.1183/13993003.congress-2016.PA2897 VO 48 IS suppl 60 A1 Karen Ward A1 Helen Ashcroft A1 Verity Ford A1 Sara Wordingham-Baker A1 Biswajit Chakrabarti A1 Robert Angus A1 Nick Duffy A1 Robert Parker YR 2016 UL http://erj.ersjournals.com/content/48/suppl_60/PA2897.abstract AB Background: Wireless monitoring and titration of NIV (non-invasive ventilation) has been reported in one European centre (Pinto et al. J Neurol Neurosurg Psychiatry 2010); this is now available in a standard UK device.Aim: Pilot evaluation of the effectiveness of therapy, data transfer and remote modification.Methods: Eligible patients included those new to or already using NIV, excluding patients with likely ventilator dependency; 3 patients were issued Lumis 150 VPAP ST-A devices for trial (Resmed, UK).Results: Ventilator interaction data has been visible since initiation.Patient A: Leak was seen to exceed recommendations for this device and circuit (24LPM), with a median of 59.2LPM. Mask and setting change has been undertaken and monitored remotely, avoiding inpatient titration or 110km travel; median leak is now 5.2LPM.Patient B: Satisfactory compliance (all days >4hours), tidal volume (median 944ml) and minute ventilation (median 13.5LPM) seen; no modifications made.Patient C: Symptomatic sleep disordered breathing and poor compliance with CPAP led to trial of NIV. Remote data shows that NIV was used 19 times in 28 days (average 2.1h/night). Tidal volumes are satisfactory (median 697ml) but continued low compliance has guided input. ABCAge, years625765DiagnosisKyphoscoliosisDiaphragmatic insufficiencyOHSMean compliance (hours/night)7.88.02.1Median leak (LPM)59.20.320.5Median tidal volume (ml)979944697Data are number, mean or median. LPM: litres per minute; OHS: obesity hypoventilationPatient DataConclusion: Remote NIV titration and monitoring is available and effective, allowing targeted input and potential streamlining of initiation and follow-up.