TY - JOUR T1 - Incidence of TB Lymphadenopathy on EBUS TBNA in renal failure v/s non renal failure patients JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2016.PA3856 VL - 48 IS - suppl 60 SP - PA3856 AU - Umang Shah AU - Nevin Kishore AU - Dinesh Khullar AU - Nitin Dayal AU - Palak Brahmbhatt Y1 - 2016/09/01 UR - http://erj.ersjournals.com/content/48/suppl_60/PA3856.abstract N2 - Aim: Newly arising enlarged or hyper metabolic mediastinal / hilar lymph nodes in patients with previously diagnosed renal failure raise suspicion of Tuberculosis which is more prevalent among immune compromised patients (those on dialysis) and recipients of organ transplants. We aimed to determine incidence of Tuberculosis in these patients.Methodology: Retrospective analysis was performed in 70 patients with proven renal failure and non-renal failure who underwent EBUS TBNA in 2015.Results: EBUS TBNA in 35 renal failure cases revealed Granuloma positive in 20 (57.14%), Reactive lymphadenitis in 12 (34.28%) and Anthracosis in 3 (8.57%) whereas results in 35 non-renal failure cases revealed Granuloma positive in 17 (48.57%), Reactive lymphadenitis in 10 (28.57%), Anthracosis in 2 (5.71%), Malignancy in 4 (11.42%) and Inconclusive results in 2 (5.71%). In Renal failure cases, AFB positive in Granuloma positive revealed 13 (65%) and AFB negative was 7 (35%) whereas in non-renal failure cases, AFB positive in Granuloma positive revealed 15 (88.23%) and AFB negative was 2 (11.76%). P value is 0.1371.The sensitivity, specificity, positive predictive value and negative predictive value of EBUS TBNA for Granuloma positive were 57.14%, 51.43%, 54.05% and 54.55%. When both AFB positive and AFB negative cases were considered, sensitivity, specificity, positive predictive value and negative predictive value of EBUS TBNA were 37.14%, 54.29%, 44.83% and 46.34%.Conclusions: The incidence of Tuberculosis in the allograft recipient and renal failure is relatively high as compared to Non renal failure cases. EBUS TBNA is safe, minimally invasive method for diagnosis and assessment of Mediastinal LNs. ER -