RT Journal Article SR Electronic T1 Does the neutrophil-to-lymphocyte ratio have any importance between subjects with obstructive sleep apnea syndrome with obesity and without obesity? JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA2298 DO 10.1183/13993003.congress-2016.PA2298 VO 48 IS suppl 60 A1 Fulsen Bozkus A1 Nursel Dikmen A1 Anil Samur YR 2016 UL http://erj.ersjournals.com/content/48/suppl_60/PA2298.abstract AB Obesity and obesity related diseases are on the increase worldwide, especially within developed countries. An increase in the incidence of OSAS (obstructive sleep apnoea syndrome) has been seen due to the reported association between OSAS and obesity.The aim is to evaluate neutrophil to lymphocyte ratio(NLR), which is a easily measured parameter of systemic inflammation in OSAS subjects with and without obesity. 155 subjects were assigned to four different groups according to their body mass indices. Comparisons of white blood cell, neutrophil, lymphocyte, NLR values and anthropometric measurements were done for each group. The NLR and neutrophil counts of group 4 were statistically significant and higher than those of groups 1, 2 and 3. The lymphocyte counts of group 4 were the lowest amongst all groups, these values were lower than the lymphocyte counts of groups 1, 2 and 3 with statistically significant differences .Group 1 ControlGroup 2 Normal OSAGroup 3 Overweight OSAGroup 4 Obesity OSAP ValueNeutrophil count (mean ±SD; 103/μ)3.57±0.284.43±0.274.67±0.376.34±0.570,001Lymphocyte count (mean ±SD; 103/μ)2.31±0.152.76±0.172.59±0.272.12±0.0630,001Leukocyte count (mean ± SD; 103/μ)6.84±0.357.27±0.478.46±0.329.46±0.360,001NLR (mean ±SD)1.55±0.161.59±0.151.83±0.302.98±0.290,001NLR =neutrophil-to-lymphocyte ratio, WBC = white blood cellFull blood count of the groupsThe NLR ratio was found to be increasing by obesity grade and reveals that the associated inflammatory response also increases.