TY - JOUR T1 - PROOF: A prospective observational registry to describe the disease course and outcomes of idiopathic pulmonary fibrosis patients in a real-world clinical setting in Belgium and Luxembourg: Exposure in the interim report of 175 IPF patients JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2016.OA4572 VL - 48 IS - suppl 60 SP - OA4572 AU - Wim Wuyts AU - Benjamin Bondue AU - Caroline Dahlqvist AU - Hans Slabbynck AU - Marc Schlesser AU - Geert Verleden AU - Karl Richir AU - Christophe Compere AU - Natacha Gusbin AU - Guy Joos AU - Sofie Maddens Y1 - 2016/09/01 UR - http://erj.ersjournals.com/content/48/suppl_60/OA4572.abstract N2 - Introduction: Idiopathic pulmonary fibrosis (IPF) is a progressive and irreversible fatal disease. An observational registry of IPF patients (PROOF registry) was initiated to collect data from routine clinical visits and monitor IPF development.Aims and objectives: The PROOF registry aims to describe the disease course and outcomes in IPF pts in a real-world setting. This abstract focuses on exposureMethods: Data from IPF patients include demographic information, medical history, pulmonary function data, high-resolution computed tomography, quality of life and previous/current treatments.Results: From October 2013 to august 2015 175 pts have been enrolled. The vast majority of IPF patients were diagnosed in an experienced multidisciplinary team during multidisciplinary discussion. Exposure was thoroughly searched for and systematically recorded. In almost half of the patients (43%) a significant work-related exposure was recorded and in 34% of patients a domestic exposure was recorded. The most frequently occurring occupational exposures were asbestos (13%), paint/chemicals (11%) and metal dusts (8%). In the domestic environment exposure to birds (17%) was most common.Conclusions: We describe the recorded exposure of patients diagnosed with IPF in a multidisciplinary meeting. These data show that work related and/or domestic exposure might be more common than originally thought. A positive exposure history often makes a diagnosis of IPF more difficult, however here again multidisciplinary discussion is crucial to come to a confident diagnosis. ER -