RT Journal Article
SR Electronic
T1 The King's brief interstitial lung disease (K-BILD) questionnaire; an updated minimal important difference
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP PA808
DO 10.1183/13993003.congress-2016.PA808
VO 48
IS suppl 60
A1 Sinha, Aish
A1 Patel, Amit S.
A1 Siegert, Richard
A1 Bajwah, Sabrina
A1 Keir, Greg
A1 Gordon, Patrick
A1 Steer, Sophia
A1 Maher, Toby M.
A1 Renzoni, Elisabetta A.
A1 Wells, Athol U.
A1 Higginson, Irene J.
A1 Birring, Surinder S.
YR 2016
UL http://erj.ersjournals.com/content/48/suppl_60/PA808.abstract
AB Introduction: The K-BILD is a validated HRQOL questionnaire. We previously reported the MID is 8 units. Item responses are now transformed to logits rather than using raw responses, as this is potentially a more linear scale (Patel A, JCE 2015;68;1019). The aim of this study was to re-evaluate the K-BILD MID using the logit scale.Methods: 57 patients with ILD (17-IPF) completed the K-BILD on 2 occasions. At the second visit patients also completed a Global rating of change of health status questionnaire (GRCQ). The MID was calculated as the mean of 4 different methods (anchors): GRCQ, 7-12% change in FVC, 1 SEM and effect size (ES) of 0.3.Results: The mean(SD) K-BILD Total score for all patients was 55.3(15.6). 36 patients reported a change in their condition on the GRCQ. There was a significant change in K-BILD score in patients reporting a change in GRCQ; mean(SD) 57.0(13.6) vs. 50.0(9.7); mean diff 7.0; 95% CI 3.0 to 11.0; p<0.01. The change in K-BILD score correlated with the GRCQ; r=-0.49, p<0.01. The mean(range) K-BILD total score MID was 5(4-7). MID AnchorMean MIDGRCQFVC 7-12%1 SEMES 0.3K-BILD Psychological5.3 (17.8)7.4 (5.6)5.85.86K-BILD Breathlessness and Activities8.3 (18.3)6.9 (12.0)6.96.17K-BILD Chest11.2 (19.4)13.7 (21.5)12.37.111K-BILD Total6.7 (13.2)6.1 (7.0)3.84.75Conclusion: In conclusion K-BILD is a responsive tool for longitudinal assessment of HRQOL in patients with ILD. The MID of the K-BILD Total score is a 5 unit change.