PT  - JOURNAL ARTICLE
AU  - Sinha, Aish
AU  - Patel, Amit S.
AU  - Siegert, Richard
AU  - Bajwah, Sabrina
AU  - Keir, Greg
AU  - Gordon, Patrick
AU  - Steer, Sophia
AU  - Maher, Toby M.
AU  - Renzoni, Elisabetta A.
AU  - Wells, Athol U.
AU  - Higginson, Irene J.
AU  - Birring, Surinder S.
TI  - The King's brief interstitial lung disease (K-BILD) questionnaire; an updated minimal important difference
AID  - 10.1183/13993003.congress-2016.PA808
DP  - 2016 Sep 01
TA  - European Respiratory Journal
PG  - PA808
VI  - 48
IP  - suppl 60
4099  - http://erj.ersjournals.com/content/48/suppl_60/PA808.short
4100  - http://erj.ersjournals.com/content/48/suppl_60/PA808.full
SO  - Eur Respir J2016 Sep 01; 48
AB  - Introduction: The K-BILD is a validated HRQOL questionnaire. We previously reported the MID is 8 units. Item responses are now transformed to logits rather than using raw responses, as this is potentially a more linear scale (Patel A, JCE 2015;68;1019). The aim of this study was to re-evaluate the K-BILD MID using the logit scale.Methods: 57 patients with ILD (17-IPF) completed the K-BILD on 2 occasions. At the second visit patients also completed a Global rating of change of health status questionnaire (GRCQ). The MID was calculated as the mean of 4 different methods (anchors): GRCQ, 7-12% change in FVC, 1 SEM and effect size (ES) of 0.3.Results: The mean(SD) K-BILD Total score for all patients was 55.3(15.6). 36 patients reported a change in their condition on the GRCQ. There was a significant change in K-BILD score in patients reporting a change in GRCQ; mean(SD) 57.0(13.6) vs. 50.0(9.7); mean diff 7.0; 95% CI 3.0 to 11.0; p<0.01. The change in K-BILD score correlated with the GRCQ; r=-0.49, p<0.01. The mean(range) K-BILD total score MID was 5(4-7). MID AnchorMean MIDGRCQFVC 7-12%1 SEMES 0.3K-BILD Psychological5.3 (17.8)7.4 (5.6)5.85.86K-BILD Breathlessness and Activities8.3 (18.3)6.9 (12.0)6.96.17K-BILD Chest11.2 (19.4)13.7 (21.5)12.37.111K-BILD Total6.7 (13.2)6.1 (7.0)3.84.75Conclusion: In conclusion K-BILD is a responsive tool for longitudinal assessment of HRQOL in patients with ILD. The MID of the K-BILD Total score is a 5 unit change.