@article {PorzioOA3331, author = {Michele Porzio and Andrea Mazzetta and Romain Kessler and Anne Olland}, title = {LATE-BREAKING ABSTRACT: Long-term consequences of central airways stenosis after lung transplantation}, volume = {48}, number = {suppl 60}, elocation-id = {OA3331}, year = {2016}, doi = {10.1183/13993003.congress-2016.OA3331}, publisher = {European Respiratory Society}, abstract = {Central airways stenosis after lung transplantation is a frequent but poorly understood complication. Objectives of our study were to evaluate if stenosis was associated with worse outcomes after transplant. Lung transplant recipients of a single center (Strasbourg, France) between April 2009 and August 2014 were retrospectively reviewed. 191 lung transplants were realized: 175 bilateral lung transplants, 15 single lung, 1 cardiopulmonary. 22 (13\%) developed central airway stenosis requiring endobronchial treatment. All these patients were treated by endoscopic dilatation with balloon; 9 patients (43\%) needed endobronchial stents. Survival in recipients with or without central airway stenosis was not different. Respiratory infections and duration of hospitalization were significantly increased in recipients with airway stenosis (p=0,006, p=0,048 respectively). Respiratory function tests showed a decreased forced expiratory volume in one second (FEV1, \%pred) in recipients with central airway stenosis, despite endoscopic treatment. Central airway stenosis after lung transplantation was not associated with a worse survival in our experience, but it showed an impact on long term lung function and it was a risk factor for respiratory infections.Patients (n)Stenosis (22)W/o stenosis (153)pHospitalization length of stay (days)144,23{\textpm}10996{\textpm}820.048Episodes of infection (during 18 months)2,4{\textpm}21,2{\textpm}10.006TABLE 1}, issn = {0903-1936}, URL = {https://erj.ersjournals.com/content/48/suppl_60/OA3331}, eprint = {https://erj.ersjournals.com/content}, journal = {European Respiratory Journal} }