TY - JOUR T1 - Effect of nasal high flow heated oxygen in chronic airway disease on quality of life and hospital admissions JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2016.PA3744 VL - 48 IS - suppl 60 SP - PA3744 AU - Ilanit Meijntz-Valentijn AU - M.C. Gubbelmans AU - G.J. de Vries Y1 - 2016/09/01 UR - http://erj.ersjournals.com/content/48/suppl_60/PA3744.abstract N2 - Introduction: Chronic Obstructive Pulmonary Disease is a progressive airway disease.The disease has an substantial impact on the quality of life. In case of progression of the disease, the patients would normally receive additional low-flow oxygen. Recently there is growing interest in the administration of Nasal High Flow Oxygen therapy. However there is limited experience in the Netherlands with NHFO in a long-term home situation.Aims: To investigate a positive effect of Long-term Nasal High Flow Oxygen Therapy on quality of life and frequency of hospital admissions for COPD patients.Methods: In this prospective study 16 patients with COPD GOLD III to IV and two or more hospital admissions were included. A comparison between pre and post start of NHFO was made. They received NHFO at home for a period of six to twelve month. Quality Of Life was measured using the SGRQ.Results: The results regarding the Quality Of Life measured by the SGRQ can be divided in the three subcategories. On the domain symptom perception a significant difference (from 88,18 to 78,9) with a p-value of 0.05 has been found. On the domain activity and the domain impact no significant differences (respectively 08,44 and 00,22) were found. It appeared that the patients had less hospital admissions after six months, which is confirmed by a difference of 1,71 and a p-value of 0,01.Conclusions: Long-term Nasal High Flow Oxygen Therapy (NHFO) applied to patients with COPD resulted in a significant improvement in the subcategory symptom perception of the Quality Of Life Questionnaire. Furthermore, a significant decrease in hospital admissions was seen after six months compared to before the start of NHFO. ER -