RT Journal Article SR Electronic T1 The impact of comorbidities on pulmonary rehabilitation outcomes in patients with COPD JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA3790 DO 10.1183/13993003.congress-2016.PA3790 VO 48 IS suppl 60 A1 Kallianos, Anastasios A1 Charikiopoulou, Maria A1 Arapis, Ioannis A1 Velentza, Lemonia A1 Kokkolios, Alexandros A1 Bletsa, Maria A1 Trakada, Georgia A1 Rapti, Aggeliki YR 2016 UL http://erj.ersjournals.com/content/48/suppl_60/PA3790.abstract AB INTRODUCTION: COPD is a disease with comorbidities, which contribute to morbidity and mortality, independently severity.AIM: Study comorbidity patterns of COPD patients, correlation between comorbidities and outcomes of pulmonary rehabilitation.METHODS: 32 patients with COPD, underwent a comprehensive pulmonary rehabilitation program, divided into two groups, according to comorbidities. Patients with none or one comorbidity (n=11) compared to those with two or more , in terms of their response to parameters: mMRC, CAT, SGRQ, 6MWT and CPET. As cardiovascular and metabolic comorbidities were the most frequent (68.8% and 53.1% respectively), we studied the outcomes of the program between two more subgroups of patients, those who presented and those who didn't present those two comorbidities.RESULTS: The presence of comorbidity was reported (n=28, 87.5%) and more frequent were cardiovascular, metabolic, musculoskeletal, psychological, gastroenterological, cancers and sleep disorders. The outcomes of the subgroup of patients with none or one comorbidity and the subgroup of patients with two or more comorbidities did not present statistically significant difference to the following parameters: dyspnea (mMRC , CAT), quality of life (SGRQ),exercise capacity (6MWT). Only significant change was observed on Cardiopulmonary Exercise Testing, where V02MAX showed an important percentage increase of 25.7% in the subgroup of patients with none or one comorbidity compared to the subgroup of patients with two or more (p=0.024).CONCLUSIONS: Pulmonary Rehabilitation in COPD seems to benefit all the subgroups of patients, independently of the presence, the number or the nature of their comorbidities.