PT  - JOURNAL ARTICLE
AU  - Ksenia Nazarenko
AU  - Yuri Feschenko
AU  - Liudmyla Iashyna
AU  - Viktoria Ignatieva
AU  - Svitlana Opimah
AU  - Svitlana Moskalenko
AU  - Natalia Diachenko
TI  - Effect of auto-CPAP therapy on parameters of rhinomanometry in patients with COPD combined with OSAHS
AID  - 10.1183/13993003.congress-2016.PA647
DP  - 2016 Sep 01
TA  - European Respiratory Journal
PG  - PA647
VI  - 48
IP  - suppl 60
4099  - http://erj.ersjournals.com/content/48/suppl_60/PA647.short
4100  - http://erj.ersjournals.com/content/48/suppl_60/PA647.full
SO  - Eur Respir J2016 Sep 01; 48
AB  - Background:. Patients with “overlap syndrome” (COPD+OSAHS) often have structural and functional pathology of upper airways, that aggravate course of COPD and decrease their health status. Aim of study - to investigate structural and functional pathology of upper airwaysand assess the effect of auto-CPAP therapy on parameters of rhinomanometry in patients with COPD combined with OSAHS.Materials and methods: general clinical and otolaryngological examination, front active rhinomanometry(“Cardinal Health” (Germany).20 patients with COPD in combination with OSAHS (16 male and 4 female, mean age (53,7 ± 3,0) years , FEV1 – (61,6 ± 3,2) %, FEV1/FVC – (63,2 ± 3,1) %), IAH – (25,7 ± 6,4) / h.Results: The most common anato.mical peculiarities in the upper respiratory tract in studied patients were increase of lingual tonsil – in 12 ( 60.0 %) and hyperplasia of the soft palate – in 10 ( 50.0 %) patients, increasing in the soft palate uvula – in 9 ( 45.0 %), hypertrophy of the tonsils – in 6 (30.0 %) and physiological narrowing of the nasal passages – in 4 ( 20.0% ) patients. The combination of different anatomical features and pathological processes occurred in 14 (70,0 %) of 20 patients. Following the appointment of a 14-day course of auto- CPAP therapy was defined significant increase in rhinomanometry indices: total nasal flow – as during exhalation from (249,0 ± 60,6 ) ml/s to (664,0 ± 66,4) ml/s, p < 0,05, and during inspiration from (298,6 ± 56,9) ml/s to (624,3 ± 80,8) ml/s, p < 0,05.Conclusion: Course auto-CPAP therapy improve nasal permeability in patients with COPD combined with OSAHS.