RT Journal Article SR Electronic T1 FEV1%pred and BMI are weak predictors for clinical outcome after pulmonary rehabilitation in COP JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA3592 DO 10.1183/13993003.congress-2016.PA3592 VO 48 IS suppl 60 A1 Janneke Dilling A1 Hester van der Vaart A1 Johan Wempe YR 2016 UL http://erj.ersjournals.com/content/48/suppl_60/PA3592.abstract AB Introduction: Pulmonary rehabilitation (PR) is a fundamental part of the integrated care of people with chronic obstructive pulmonary disease (COPD). Little is known about characteristics which predict PR outcome.Aim: To investigate whether baseline characteristics may predict the clinical response as measured by Clinical COPD Questionnaire (CCQ), COPD Assessment Test (CAT) and Endurance Shuttle Walk Test (ESWT).Method: 352 COPD patients were included in this study. Static and dynamic lungfunction, body mass index (BMI), cycle ergometry with blood gases, incremental shuttle walk test, ESWT, CCQ and CAT were measured at the start of PR. Subjects followed a program with exercise training, education and psychological interventions.After 9 weeks, ESWT, CCQ en CAT were repeated.As a minimal important clinical difference (MCID) we used 0.4 for the CCQ and 2 for the CAT.Results: View this table:Baseline characteristicsView this table:Changes from baselineA small significant correlation (Spearman) was found between Δ ESWT and FEV1%pred (ρ=0.168), between Δ ESWT and BMI (ρ=0.272) and between Δ CCQ and FEV1%pred (ρ=0.219).The proportion of patients improving > MCID was 73% (CAT) and 73% (CCQ). Responders were not different from non-responders with respect to the baseline characterics and PaO2 or PaCO2 values.Conclusion: In our population, FEV1%pred and BMI are weak predictors for the outome of PR.