TY - JOUR T1 - Silent aspiration in patients with exacerbation of COPD JF - European Respiratory Journal JO - Eur Respir J SP - 570 LP - 573 DO - 10.1183/13993003.00007-2016 VL - 48 IS - 2 AU - Zeguang Zheng AU - Zhida Wu AU - Ni Liu AU - Ping Chen AU - Peng Hou AU - Xinni Wang AU - Yimin Fu AU - Weijian Liang AU - Rongchang Chen Y1 - 2016/08/01 UR - http://erj.ersjournals.com/content/48/2/570.abstract N2 - Patients with chronic obstructive pulmonary disease (COPD) are susceptible to aspiration, probably due to discoordination between breathing and swallowing, cricopharyngeal muscle dysfunction, and changes in lung volume [1, 2]. Terada et al. [3] found a significantly higher prevalence of an abnormal swallowing reflex in patients with COPD than in healthy controls. Shaker et al. [4] found that patients with acute exacerbation of COPD (AECOPD) have a higher risk of aspiration. In this cross-sectional study, using the technetium-99m–sulfur colloid (99mTc-SC) salivary scintigraphy method that is believed to be more sensitive than techniques using in previous studies, the prevalence and risk factors of silent aspiration in hospitalised AECOPD patients was studied.Radionuclide imaging of silent aspiration http://ow.ly/s3pz300hiSNWe would like to express our gratitude to all of those who assisted with the preparation of this manuscript, particularly to Guangqiao Zeng (State Key Laboratory of Respiratory Disease, Guangzhou, China) for helpful contributions to the translation and editing of this article. ER -