TY - JOUR T1 - Computed tomography-derived pathological phenotypes in COPD JF - European Respiratory Journal JO - Eur Respir J SP - 10 LP - 13 DO - 10.1183/13993003.00958-2016 VL - 48 IS - 1 AU - William MacNee Y1 - 2016/07/01 UR - http://erj.ersjournals.com/content/48/1/10.abstract N2 - Chronic obstructive pulmonary disease (COPD) is considered to be a complex, multicomponent, heterogeneous disease, the pathology, clinical and functional presentation of which vary greatly between individual patients despite similar degrees of airflow limitation [1]. COPD has therefore been considered to have distinct phenotypes that represent a single or combination of disease attributes that describe differences between individuals with COPD as they relate to clinically meaningful outcomes such as symptoms, exacerbations, rate of disease progression or death [2]. Importantly, these phenotypes of COPD may require different targeted treatment strategies [3].There is a need to reach a consensus on the most appropriate method for quantifying emphysema and airways by CT http://ow.ly/YCKP300tQQi ER -