RT Journal Article SR Electronic T1 Characteristics of effective self-management interventions in patients with COPD: individual patient data meta-analysis JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP ERJ-01860-2015 DO 10.1183/13993003.01860-2015 A1 Nini H. Jonkman A1 Heleen Westland A1 Jaap C.A. Trappenburg A1 Rolf H.H. Groenwold A1 Erik W.M.A. Bischoff A1 Jean Bourbeau A1 Christine E. Bucknall A1 David Coultas A1 Tanja W. Effing A1 Michael Epton A1 Frode Gallefoss A1 Judith Garcia-Aymerich A1 Suzanne M. Lloyd A1 Evelyn M. Monninkhof A1 Huong Q. Nguyen A1 Job van der Palen A1 Kathryn L. Rice A1 Maria Sedeno A1 Stephanie J.C. Taylor A1 Thierry Troosters A1 Nicholas A. Zwar A1 Arno W. Hoes A1 Marieke J. Schuurmans YR 2016 UL http://erj.ersjournals.com/content/early/2016/04/28/13993003.01860-2015.abstract AB It is unknown whether heterogeneity in effects of self-management interventions in patients with chronic obstructive pulmonary disease (COPD) can be explained by differences in programme characteristics. This study aimed to identify which characteristics of COPD self-management interventions are most effective.Systematic search in electronic databases identified randomised trials on self-management interventions conducted between 1985 and 2013. Individual patient data were requested for meta-analysis by generalised mixed effects models.14 randomised trials were included (67% of eligible), representing 3282 patients (75% of eligible). Univariable analyses showed favourable effects on some outcomes for more planned contacts and longer duration of interventions, interventions with peer contact, without log keeping, without problem solving, and without support allocation. After adjusting for other programme characteristics in multivariable analyses, only the effects of duration on all-cause hospitalisation remained. Each month increase in intervention duration reduced risk of all-cause hospitalisation (time to event hazard ratios 0.98, 95% CI 0.97–0.99; risk ratio (RR) after 6 months follow-up 0.96, 95% CI 0.92–0.99; RR after 12 months follow-up 0.98, 95% CI 0.96–1.00).Our results showed that longer duration of self-management interventions conferred a reduction in all-cause hospitalisations in COPD patients. Other characteristics are not consistently associated with differential effects of self-management interventions across clinically relevant outcomes.Increasing duration of self-management interventions reduces risk of all-cause hospitalisations in patients with COPD http://ow.ly/YVw9E