TY - JOUR T1 - High-flow nasal oxygen for bronchoalveolar lavage in acute respiratory failure patients JF - European Respiratory Journal JO - Eur Respir J SP - 1283 LP - 1286 DO - 10.1183/13993003.01883-2015 VL - 47 IS - 4 AU - Béatrice La Combe AU - Jonathan Messika AU - Vincent Labbé AU - Keyvan Razazi AU - Bernard Maitre AU - Benjamin Sztrymf AU - Didier Dreyfuss AU - Muriel Fartoukh AU - Jean-Damien Ricard Y1 - 2016/04/01 UR - http://erj.ersjournals.com/content/47/4/1283.abstract N2 - Fiberoptic bronchoscopy with bronchoalveolar lavage (BAL) holds significant risks of oxygenation deterioration [1]. Among various means to improve oxygenation during BAL, noninvasive positive pressure ventilation (NPPV) has received the greatest attention [2, 3]. However, NPPV is a time-consuming and very demanding technique. High-flow nasal cannula oxygen therapy (HFNC) has emerged as a technique for noninvasive respiratory management of hypoxaemic patients [4]. In patients with acute respiratory failure (ARF), its beneficial effects have been shown in various populations [5], and its effectiveness and superiority over NPPV and conventional oxygenation recently demonstrated [6]. Its use has also been described during bronchoscopy in non-hypoxaemic [7] and in hypoxaemic patients in comparison with NPPV [8]. However, bronchoscopy was performed with an open mouth in both studies, which considerably reduces HFNC efficacy [9]. Thus, we aimed to determine HFNC's effectiveness during nasal bronchoscopy with BAL in patients with ARF along with BAL's feasibility and yield.HFNC is an effective and safe method of oxygenation during nasal bronchoscopy with BAL in hypoxaemic ARF patients http://ow.ly/XAmtZJonathan Messika, Muriel Fartoukh and Jean-Damien Ricard are members of the GREPI (French Group for Research and Education in Respiratory Infectious Diseases). ER -