TY - JOUR T1 - Does mass spectrometric breath analysis detect <em>Pseudomonas aeruginosa</em> in cystic fibrosis? JF - European Respiratory Journal JO - Eur Respir J SP - 994 LP - 997 DO - 10.1183/13993003.00944-2015 VL - 47 IS - 3 AU - Rishi Pabary AU - Juzheng Huang AU - Sacheen Kumar AU - Eric W.F.W. Alton AU - Andrew Bush AU - George B. Hanna AU - Jane C. Davies Y1 - 2016/03/01 UR - http://erj.ersjournals.com/content/47/3/994.abstract N2 - Pseudomonas aeruginosa associated with increased morbidity and mortality in cystic fibrosis (CF) can be eradicated if detected early; however, prompt detection is problematic in children and non-expectorating adults as oropharyngeal cultures lack sensitivity [1]. We previously reported that 20% of children with negative oropharyngeal cultures isolated P. aeruginosa on bronchoalveolar lavage [2], but this invasive technique cannot be performed frequently. Hence, there is an urgent need for a noninvasive screening test for lower airways infection in CF; therefore, we propose that exhaled volatile organic compounds (VOC) may be useful biomarkers.Detecting P. aeruginosa infection is problematic; breath analysis shows promise but requires optimisation http://ow.ly/WE1H2 ER -