TY - JOUR T1 - Treatable traits: toward precision medicine of chronic airway diseases JF - European Respiratory Journal JO - Eur Respir J SP - 410 LP - 419 DO - 10.1183/13993003.01359-2015 VL - 47 IS - 2 AU - Alvar Agusti AU - Elisabeth Bel AU - Mike Thomas AU - Claus Vogelmeier AU - Guy Brusselle AU - Stephen Holgate AU - Marc Humbert AU - Paul Jones AU - Peter G. Gibson AU - Jørgen Vestbo AU - Richard Beasley AU - Ian D. Pavord Y1 - 2016/02/01 UR - http://erj.ersjournals.com/content/47/2/410.abstract N2 - Asthma and chronic obstructive pulmonary disease (COPD) are two prevalent chronic airway diseases that have a high personal and social impact. They likely represent a continuum of different diseases that may share biological mechanisms (i.e. endotypes), and present similar clinical, functional, imaging and/or biological features that can be observed (i.e. phenotypes) which require individualised treatment. Precision medicine is defined as “treatments targeted to the needs of individual patients on the basis of genetic, biomarker, phenotypic, or psychosocial characteristics that distinguish a given patient from other patients with similar clinical presentations”. In this Perspective, we propose a precision medicine strategy for chronic airway diseases in general, and asthma and COPD in particular.A discussion of the concept of “treatable traits” as a way towards precision medicine of chronic airway diseases http://ow.ly/UbJAm ER -