PT  - JOURNAL ARTICLE
AU  - Agusti, Alvar
AU  - Bel, Elisabeth
AU  - Thomas, Mike
AU  - Vogelmeier, Claus
AU  - Brusselle, Guy
AU  - Holgate, Stephen
AU  - Humbert, Marc
AU  - Jones, Paul
AU  - Gibson, Peter G.
AU  - Vestbo, Jørgen
AU  - Beasley, Richard
AU  - Pavord, Ian D.
TI  - Treatable traits: toward precision medicine of chronic airway diseases
AID  - 10.1183/13993003.01359-2015
DP  - 2016 Feb 01
TA  - European Respiratory Journal
PG  - 410--419
VI  - 47
IP  - 2
4099  - http://erj.ersjournals.com/content/47/2/410.short
4100  - http://erj.ersjournals.com/content/47/2/410.full
SO  - Eur Respir J2016 Feb 01; 47
AB  - Asthma and chronic obstructive pulmonary disease (COPD) are two prevalent chronic airway diseases that have a high personal and social impact. They likely represent a continuum of different diseases that may share biological mechanisms (i.e. endotypes), and present similar clinical, functional, imaging and/or biological features that can be observed (i.e. phenotypes) which require individualised treatment. Precision medicine is defined as “treatments targeted to the needs of individual patients on the basis of genetic, biomarker, phenotypic, or psychosocial characteristics that distinguish a given patient from other patients with similar clinical presentations”. In this Perspective, we propose a precision medicine strategy for chronic airway diseases in general, and asthma and COPD in particular.A discussion of the concept of “treatable traits” as a way towards precision medicine of chronic airway diseases http://ow.ly/UbJAm