TY - JOUR T1 - Detection of pepsin in sputum: a rapid and objective measure of airways reflux JF - European Respiratory Journal JO - Eur Respir J SP - 339 LP - 341 DO - 10.1183/13993003.00827-2015 VL - 47 IS - 1 AU - Vicki Strugala AU - Andrew D. Woodcock AU - Peter W. Dettmar AU - Shoaib Faruqi AU - Alyn H. Morice Y1 - 2016/01/01 UR - http://erj.ersjournals.com/content/47/1/339.abstract N2 - The diagnostic test, Peptest (RD Biomed Ltd, Cottingham, UK), detects pepsin in expectorated saliva and is established as a simple, noninvasive measure of reflux of gastric contents. It has been used to detect pepsin A in patients with both gastro-oesophageal reflux disease (GORD) and extra-oesophageal reflux into the laryngopharynx and airways [1–5].Detection of salivary pepsin (Peptest) may be a useful adjunct in the diagnosis of airway reflux http://ow.ly/T7B0lWe gratefully acknowledge the RD Biomed Ltd technical assistance of Jeanine Fisher (Cottingham, UK), the NHS patient management of Karen Welburn and the NHS secretarial assistance of Hanka Remblance (both Centre for Cardiovascular and Metabloic Research, Hull York Medical School, University of Hull, Castle Hill Hospital, Cottingham). ER -