RT Journal Article
SR Electronic
T1 Sclerosing hemangioma of the lung: Report of 4 cases
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP PA4305
DO 10.1183/13993003.congress-2015.PA4305
VO 46
IS suppl 59
A1 I.V. Dvorakovskaya
A1 T.A. Novitskaya
A1 F.M. Mazitova
A1 I.N. Chuprov
A1 S.A. Vinnichuk
YR 2015
UL http://erj.ersjournals.com/content/46/suppl_59/PA4305.abstract
AB Sclerosing hemangioma of the lung (SGL) (pnevmotsistoma, sclerosing angioma, fibroksantoma, vascular endotelioma, alveolar angioblastoma) - a rare benign tumor, is 20-22% of operated benign tumors. SGL is more common in middle-aged women, occurs usually asymptomatic. The tumor grows slowly, often localized in the lower lobe of the lung (29.0% of cases). SGL prognosisis favorable.The Aim: The clinical and histological features of SGL.Material and methods: Investigated 3 SGL remote female 33, 37, 48 years. Complaints of cough and hemoptysis -1. CT - lung tumor. Used histological and immunohistochemical methods: hematoxylin and eosin, Alcian blue, revealing the expression of S-100 protein, vimentin, pancytokeratin, thyroid transcription factor 1, thyroglobulin, epithelial membrane antigen, desmin, Ki-67. Tumors rounded, dense consistency, with clear boundaries, 2-3.5 cm in diameter, met foci of calcification. In 1 case SGL was multiple.The Results: Microscopically in all SGL identified four histological components: papillary, solid, fibrous and vascular. A distinctive feature of all SGL was the proliferation of pneumocytes 2tipa. SGL cells round or polygonal in shape, with rounded or oval nucleus, abundant light or slightly eosinophilic cytoplasm, basophilic nucleoli occur.Conclusion: The differential diagnosis includes SGL inflammatory pseudotumor, clear cell tumor, carcinoid, bronchioles-alveolar carcinoma, and metastatic lesions. Verification of the diagnosis in the differential diagnosis SGL with a number of tumors with similar histological picture dictates the need for immunohistochemical studies. Prior to surgery followed by histological examination of the correct diagnosis has not been put.