RT Journal Article
SR Electronic
T1 Mucociliary clearance of smokers after physical effort submaximal and maximal
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP PA1878
DO 10.1183/13993003.congress-2015.PA1878
VO 46
IS suppl 59
A1 Renata Marques David
A1 Ercy Mara Cipulo Ramos
A1 Gabriel Faustino Santa Brígida
A1 Guilherme Yassuyuki Tacao
A1 Iara Buriola Trevisan
A1 Ana Paula Coelho Figueira Freire
A1 Juliana Tiyaki Ito
A1 Juliana Uzeloto de Souza
A1 Fabiano Francisco de Lima
A1 Marceli Rocha Leite
A1 Dionei Ramos
YR 2015
UL http://erj.ersjournals.com/content/46/suppl_59/PA1878.abstract
AB Background:It is known that smoking causes impaired mucociliary clearance making it more slow and inefficient in lung defense. Objective: To evaluate the acute response of the mucociliary transport smokers after submaximal and maximal physical effort. Methods: We studied 55 individuals of both sexes aged 30-50 years old, 35 smokers and 20 nonsmokers. All subjects underwent a submaximal aerobic workout using stimulus as the six-minute and how much exercise stimulus walk test used the cardiopulmonary exercise test (VO2 max). The mucocilar clearance was assessed before and after each exercise session by Saccharin Transit Time test (STT). For this, the smokers required in minimum 12 hours tobacco abstinenc before the tests, confirmed by monoximetria before and after the sessions. It was respected the minimum interval of 48 hours between sessions. Results: Comparing the two groups there was statistical difference in the STT after maximum physical effort (for nonsmokers 6.86±2.88 minutes and smokers 9.05±4.44 minutes; p= 0.0451). In intragroup analysis showed a statistically significant difference between pre and post exercise STT both submaximal as maximum being respectively for Smokers: 10.81±5.35 and 8.60±4.99 minutes (p=0.0243); 14.26±7.58 and 9.05±4.44 minutes (p=0.0009) and Non Smokers: 14.08±7.59 and 9.64±6.98 minutes (p=0.0023); 10.46±6.86 and 5.39 ± 2.88 minutes (p=0.0068). Conclusion: An independent physical workout intensity (submaximal or maximal) was able to significantly improve mucociliary clearance of nonsmokers and smokers , the latter being more benefits from the existing injury.