TY - JOUR T1 - Mucociliary clearance of smokers after physical effort submaximal and maximal JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2015.PA1878 VL - 46 IS - suppl 59 SP - PA1878 AU - Renata Marques David AU - Ercy Mara Cipulo Ramos AU - Gabriel Faustino Santa Brígida AU - Guilherme Yassuyuki Tacao AU - Iara Buriola Trevisan AU - Ana Paula Coelho Figueira Freire AU - Juliana Tiyaki Ito AU - Juliana Uzeloto de Souza AU - Fabiano Francisco de Lima AU - Marceli Rocha Leite AU - Dionei Ramos Y1 - 2015/09/01 UR - http://erj.ersjournals.com/content/46/suppl_59/PA1878.abstract N2 - Background:It is known that smoking causes impaired mucociliary clearance making it more slow and inefficient in lung defense. Objective: To evaluate the acute response of the mucociliary transport smokers after submaximal and maximal physical effort. Methods: We studied 55 individuals of both sexes aged 30-50 years old, 35 smokers and 20 nonsmokers. All subjects underwent a submaximal aerobic workout using stimulus as the six-minute and how much exercise stimulus walk test used the cardiopulmonary exercise test (VO2 max). The mucocilar clearance was assessed before and after each exercise session by Saccharin Transit Time test (STT). For this, the smokers required in minimum 12 hours tobacco abstinenc before the tests, confirmed by monoximetria before and after the sessions. It was respected the minimum interval of 48 hours between sessions. Results: Comparing the two groups there was statistical difference in the STT after maximum physical effort (for nonsmokers 6.86±2.88 minutes and smokers 9.05±4.44 minutes; p= 0.0451). In intragroup analysis showed a statistically significant difference between pre and post exercise STT both submaximal as maximum being respectively for Smokers: 10.81±5.35 and 8.60±4.99 minutes (p=0.0243); 14.26±7.58 and 9.05±4.44 minutes (p=0.0009) and Non Smokers: 14.08±7.59 and 9.64±6.98 minutes (p=0.0023); 10.46±6.86 and 5.39 ± 2.88 minutes (p=0.0068). Conclusion: An independent physical workout intensity (submaximal or maximal) was able to significantly improve mucociliary clearance of nonsmokers and smokers , the latter being more benefits from the existing injury. ER -