PT  - JOURNAL ARTICLE
AU  - Daisuke Jingu
AU  - Takehiro Yajima
AU  - Satoshi Ubukata
AU  - Makoto Shoji
AU  - Hiroshi Watanabe
AU  - Hiroshi Takahashi
TI  - Impact of the vaccination campaign on pneumococcal pneumonia after the great East Japan earthquake
AID  - 10.1183/13993003.congress-2015.PA1854
DP  - 2015 Sep 01
TA  - European Respiratory Journal
PG  - PA1854
VI  - 46
IP  - suppl 59
4099  - http://erj.ersjournals.com/content/46/suppl_59/PA1854.short
4100  - http://erj.ersjournals.com/content/46/suppl_59/PA1854.full
SO  - Eur Respir J2015 Sep 01; 46
AB  - Background: After the Great East Japan Earthquake, the respiratory infection had increased in a stricken area. In order to prevent the increase of pneumonia, the free vaccination campaign with the 23-valent pneumococcal polysaccharide vaccine was intended for residents aged over 70 from October 2011 to March 2012 in the area. In Miyagi prefecture, the vaccine coverage had risen from 17% to 46%.Objectives: The aim was to examine the impact of the earthquake and the following vaccination campaign on pneumococcal pneumonia in adult.Methods: We surveyed the occurrence of the adult pneumonia in our hospital between January 2010 and December 2014 retrospectively.Results: From the next autumn of the earthquake, the number of pneumococcal pneumonia in adult had begun to increase. In the corresponding period, the vaccination campaign was started. Although the rate of pneumococcal pneumonia in all adult pneumonia accounted for about 40% at the beginning of the campaign, it declined to almost 20% after the end of the campaign. The rate of pneumococcal pneumonia was 27.8% in 2010, 26.0% in 2011, 28.9% in 2012, 24.3% in 2013, and 22.3% in 2014. Compared with 2012 (just end of the campaign) and 2014, the rate declined significantly (p=0.009). The mortality rate of pneumococcal pneumonia was 3.0% in 2010, 4.7% in 2011, 8.0% in 2012, 5.4% in 2013, and 3.8% in 2014, but there was no significant difference between 2012 and 2014 (p=0.13).Conclusions: Although the number of pneumococcal pneumonia increased from the next autumn of the earthquake, it decreased after the vaccination campaign. After the campaign, the rate of pneumococcal pneumonia declined significantly.