PT - JOURNAL ARTICLE AU - Aleksey Resahetov AU - Aleksey Elkin AU - Igor Lvov AU - Olga Shtepa AU - Dmitriy Kovalenko AU - Vadim Mosiagin AU - Vladimir Nevelskiy TI - Surgical treatmment non-small cell lung cancer in the elderly patients AID - 10.1183/13993003.congress-2015.PA4282 DP - 2015 Sep 01 TA - European Respiratory Journal PG - PA4282 VI - 46 IP - suppl 59 4099 - http://erj.ersjournals.com/content/46/suppl_59/PA4282.short 4100 - http://erj.ersjournals.com/content/46/suppl_59/PA4282.full SO - Eur Respir J2015 Sep 01; 46 AB - The role of surgical treatment NSCLC for group of elderly patients is not quite clear.The aim of study was to analyze the resalts of surgical treatment NSCLC in patients over 75 years.Methods: the clinical database consists 64 patients age 75 or older who underwent surgical treatment of NSCLC from 2009 to 2014 (group A). We compared it with similar group (group B) of 64 patients from 45 to 69 years. Mean follow up was 39 month (from 3 to 59). Sirvival was estimated using Kaplan-Maier method. Univariate and multivariate analysis were perfomed to identify significant prognostic factors related to overall and free recurrence sirvival.Resalts: The frequency of postoperative complication was 40% in group A and 25% in group B. Postoperative mortality was 3.2% in group A and 1.6% in group B. The median of sirvival was equal in both groups - 24 month. 3-years overall and free recurrence sirvival were 50% and 43% in group A, 55 and 54% in group B respectively. For elderly patients the results were significantly influenced by comorbid background. All elderly patients underwent thorough study of coronary and cerebral circulation and its surgical correction as the first step if needed. Surgery of NSCLC was carried out as the second step after 4-8 weeks. The treatment results were significantly better after vessels of neck and coronary stenting or by-pass (p=0.001). Recurrence free and overall sirvival were significant worsen after wedge resection and pneumonectomy (p=0.005, p=0.02).Conclusion: Surgery of NSCLC for elderly patients should be provided taking into account the comorbid background after inproving coronary and cerebral circulation if necessary. Preferens should be given to lobectomies and segmentectomy.