RT Journal Article
SR Electronic
T1 Ventilatory analysis during 6MWT gives relevant information about exercise limitation in COPD
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP PA2237
DO 10.1183/13993003.congress-2015.PA2237
VO 46
IS suppl 59
A1 Bernardi, Eva
A1 Stiz, Benedetta
A1 Angelini, Sergio
A1 Contoli, Marco
A1 Cogo, Annalisa
YR 2015
UL https://publications.ersnet.org//content/46/suppl_59/PA2237.abstract
AB It's well known that exercise performance of COPD is limited by ventilation (VE), in particular the inability of further increasing VE. The 6-minute walk test (6MWT) is the most established field exercise test. The VE analysis during 6MWT can be an useful tool to better understand the causes of exercise limitation in COPD.Aim: to investigate the respiratory responses during 6MWT in untrained COPD.Methods: 37M, 12F (age 48-85 yr) performed spirometry and 6MWT equipped with Spiropalm®, an instrument which allow VE measurement breath by breath and a continuous monitoring of heart rate and SpO2. Breathing reserve (BR) is calculated by the instrument as the difference between maximal voluntary ventilation (FEV1x40) and max VE reached during the test.Results: Subjects were classified according to FEV1 as % of predicted. 6MWT data are reported in Table 1. View this table:Table 1 We found a correlation between FEV1 and BR (r=0.86, p<0.001); BR and oxygen desaturation [basal SpO2 minus final SpO2 (r=-0.38, p=0.009)]; BR and dyspnea Borg score (r=-0.36, p=0.01). A correlation between distance and dyspnea was also found (r=-055, p<0.001).Conclusion: BR is a mark of exercise limitation, therefore the analysis of VE during 6MWT can be a simple tool contributing to explain exercise limitation in COPD even in the absence of more sophisticated tests.