RT Journal Article
SR Electronic
T1 Cardiovascular status of patients with a severe form of COPD
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP OA3289
DO 10.1183/13993003.congress-2015.OA3289
VO 46
IS suppl 59
A1 Barbora Novotna
A1 Vladimir Koblizek
A1 Michal Svoboda
A1 Jan Svancara
A1 Karel Hejduk
A1 Jiri Jarkovsky
A1 Michal Kopecky
A1 Rudolf Praus
A1 Zuzana Zbozinkova
A1 Marek Putinsky
A1 Jaromir Zatloukal
A1 Patricie Popelkova
A1 Tomas Dvorak
A1 Petr Safranek
A1 Ondrej Sobotik
A1 Alena Vlachova
A1 Petr Vanik
A1 Zuzana Liptakova
A1 Lucie Heribanova
A1 Blanka Snelerova
A1 Pavlina Musilova
A1 Maria Majerciakova
A1 Tomas Vencalek
A1 Eva Kocova
A1 Onderj Kudela
A1 Katerina Neumannova
A1 Kristian Brat
A1 Eva Volakova
A1 Frantisek Salajka
YR 2015
UL http://erj.ersjournals.com/content/46/suppl_59/OA3289.abstract
AB Introduction and Aims: COPD is a heterogeneous syndrome marked by pulmonary obstruction and the presence of multiple comorbidities. The high incidence of cardiovascular disease in patients with COPD may be the result of common risk factors, particularly smoking, systemic inflammation and hypoxia.The aim of this work is to examine the cardiovascular status of patients with a severe form of COPD (post-BD FEV1 < 60%).Method: The analyzed data is taken from The Czech Multicenter Database of COPD[1], a prospective study. This is the first-stage analysis at enrollment.Results: The presence of cardiovascular disease was analyzed in 343 patients. Ischemic heart disease (IHD) was present in 25.9%, heart failure (HF) 13.7%, atrial fibrillation 13.1% and hypertension 53.9%. Cachexic patients were less likely to have hypertension and HF (p= 0.055, p=0.002 respectively). The presence of IHD was statistically significant in patients with Asthma COPD overlap syndrome (p= 0.035). The incidence of hypertension was most significant in the D category (GOLD 2011) (57.3%, p=0.036). The use of cardiovascular medications was monitored; Diuretics 38.5%, ACEI 32.9%, Antiaggregants 32.7%, Statins 28.9%, Calcium antagonists 21.3%, Amiodarone 5.5%. Betablockers are used by 23%, out of which 2.4% used a known non-selective betablocker.Conclusions: Some COPD phenotypes seem to have a higher prevalence to certain types of comorbidities. Due to the high prevalence of heart disease in COPD patients, cardiovascular diseases should be actively searched for in clinical practice. NCT 01923051. 1. Novotna B et al. Czech multicenter research database of severe COPD. Int J Chron Obstruct Pulmon Dis. 2014 Nov 10;9:1265-74.