PT  - JOURNAL ARTICLE
AU  - Matthias Held
AU  - Katharina Schuh
AU  - Sabine Karl
AU  - Johanna Walthelm
AU  - Stefan Baron
AU  - Christine Roth
AU  - Berthold Jany
TI  - Long-term improvement of pulmonary haemodynamics and exercise capacity in patients with pulmonary hypertension and hypoventilation following NIPPV and influence of NIPPV adherence
AID  - 10.1183/13993003.congress-2015.PA3766
DP  - 2015 Sep 01
TA  - European Respiratory Journal
PG  - PA3766
VI  - 46
IP  - suppl 59
4099  - http://erj.ersjournals.com/content/46/suppl_59/PA3766.short
4100  - http://erj.ersjournals.com/content/46/suppl_59/PA3766.full
SO  - Eur Respir J2015 Sep 01; 46
AB  - NIPPV in patients with severe pulmonary hypertension (PH) and hypoventilation improves pulmonary haemodynamics and functional capacity. Long-term observations are lacking.Aims: To investigate functional long-term outcome and haemodynamics in patients with PH due to hypoventilation and influence of NIPPV adherence.Methods: Analysis of the two year follow- up in 40 subjects with PH due to hypoventilation using NIPPV more or less than 4 hours per night and 50 % of the treatment time.Results: NIPPV use > 4h/night and > 50 % (n=28) of the treatment time led to long-term improvement of haemodynamics and functional capacity. View this table:Table 1 NIPPV use less than 4 hours per night and less than 50% (n=12) of the treatment time improved night-time CO2, but did not improve haemodynamics and exercise capacity.Conclusion: NIPPV use more than 4 h/night and more than 50 % of the treatment time leads to a significant long-term improvement of haemodynamics and exercise capacity in patients with PH due to hypoventilation.