PT  - JOURNAL ARTICLE
AU  - Carina Nunes
AU  - Jacqueline Boldorini
AU  - Anderson Camargo
AU  - Samia Rached
AU  - Rodrigo Athanazio
AU  - Fernanda Lanza
AU  - Alberto Cukier
AU  - Rafael Stelmach
AU  - Simone Dal Corso
TI  - Comparison of metabolic and ventilatory demands and perception of effort during activities of daily living in patients with non-cystic fibrosis bronchiectasis and healthy subjects
AID  - 10.1183/13993003.congress-2015.PA2629
DP  - 2015 Sep 01
TA  - European Respiratory Journal
PG  - PA2629
VI  - 46
IP  - suppl 59
4099  - http://erj.ersjournals.com/content/46/suppl_59/PA2629.short
4100  - http://erj.ersjournals.com/content/46/suppl_59/PA2629.full
SO  - Eur Respir J2015 Sep 01; 46
AB  - Introduction: We already have shown as preliminary results that patients with non-cystic fibrosis bronchiectasis (NCF-BCT) use a higher proportion of their cardiorespiratory capacity during activities of daily living (ADLs). However, comparison of physiological responses between NCF-BCQ and controls have not yet been investigated.Aim: To compare the metabolic and ventilatory demands during ADLs between adults with NCF-BCT and healthy subjects.Methods: 39 subjects (FEV1 61±26 %pred) and 20 healthy peers performed five ADLs: putting on socks, shoes, and vest; putting away different weights on a rack; sweeping a floor; carrying weight while walking (5Kg); and climbing stairs during a minute.Results: Patients reported higher dyspnea and fatigue than healthy subjects.VO2 (% max)VO2 (% max)VE (%MVV)VE (%MVV)ADLNCF-BCTControlNCF-BCTControl143±19 ∗, 131±919.5⌊14-26⌋∗,18⌊6.5-12⌋259±24∗, 239±1324.7⌊18-33⌋∗,210⌊7.7-13.6⌋391±32∗, 343±1528.0⌊19-38⌋∗,311⌊9.5-14⌋491±32 ∗58±1534.0⌊24-45⌋∗,413.7⌊17.8-11.8⌋5102±28 ∗84±2036.0⌊27-47⌋∗20⌊26-15⌋VO2: oxygen uptake in percentage of the maximum achieved in the cardiopulmonary exercise test, VE: ventilation in percentage of the maximum voluntary ventilation. ∗ p<0.05 BCT vs. control group; 1p<0.05 vs ADL2, ADL3, ADL4 and ADL5; 2p<0.05 vs ADL3, ADL4 and ADL5; 3p<0.05 vs ADL 4 and ADL5; 4p<0.05 vs ADL5; 5p<0.05 vs ADL2 e ADL3.Physiological responses during ADLs.Conclusions: Patients with NCF-BCT have high metabolic and ventilatory demands, with a higher perception of effort to perform simple daily activities when compared to healthy peers.