RT Journal Article SR Electronic T1 Central hemodynamic patterns during recovery from peak exercise JF European Respiratory Journal JO Eur Respir J FD European Respiratory Society SP PA2449 DO 10.1183/13993003.congress-2015.PA2449 VO 46 IS suppl 59 A1 Rudolf Oliveira A1 Manyoo Agarwal A1 Roza Badreslam A1 Alexander Opotowsky A1 Aaron Waxman A1 David Systrom YR 2015 UL http://erj.ersjournals.com/content/46/suppl_59/PA2449.abstract AB We hypothesized that hemodynamic recovery patterns in exercise induced pulmonary hypertension (eiPH) and pulmonary venous hypertension (eiPVH) would differ.442 consecutive invasive cardiopulmonary exercise tests at our center from 2012-2014 were reviewed. Recovery hemodynamics were available in 245.36 eiPH, 28 eiPVH and 31 age matched normal controls (NC) were identified at peak exercise. eiPVH had significantly lower HRmax vs. NC (72±13 vs. 87±11% predicted, p<0.05), persisting in recovery. mPAP remained elevated until the 2nd min recovery in all groups vs. rest (p<0.05) (figure 1A), but only 25% eiPH remained abnormal at min 1 of recovery (figure 2A). PCWP decreased to <20mmHg in 86% of eiPVH within the 1st min (figure 2B), but remained elevated throughout recovery vs. eiPH and NC (figure 1B). Cardiac output remained elevated in all groups up to min 2 of recovery vs. rest (p<0.05). Pulmonary vascular compliance was reduced at rest and remained low at peak and recovery in eiPH vs. eiPVH and NC (p<0.05) (figure 1C).eiPVH decays quickly in recovery while markers of eiPH including resistance and compliance persist. The data suggest more fixed pulmonary vascular remodeling in eiPH than in eiPVH.