RT Journal Article
SR Electronic
T1 Smoking and lung cancer: Data from a single center in Greece
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP PA4315
DO 10.1183/13993003.congress-2015.PA4315
VO 46
IS suppl 59
A1 Bostantzoglou, Clementine
A1 Vlachantoni, Iris
A1 Samitas, Konstantinos
A1 Grigoratou, Theoplasti
A1 Economidou, Erasmia
A1 Zervas, Eleftherios
A1 Kolilekas, Lykourgos
A1 Gaga, Mina
YR 2015
UL https://publications.ersnet.org//content/46/suppl_59/PA4315.abstract
AB Introduction: Greece is a country with a high prevalence of smoking but a national cancer registry has only recently been initiated and data on lung cancer are scarce.Aim - Methods: In 2012-2013, 287 patients presented to our dept with either symptoms or an abnormal finding in their chest X-ray and were diagnosed with lung cancer. This is a descriptive study, reporting data on the histological type of cancer, staging and smoking history.Results: Of the 287 patients, 246 were men (mean age 65.1, range 30-84years and 41 women (42.2, 45-82). Only 16 patients were non-smokers, 59 were ex-smokers and the remaining were current smokers with high exposure (mean history of 80pack/years). Diagnosis was confirmed histologically in 172 and by cytology only in 115 patients. SCLC was confirmed in 96 patients (33.3%), adenocarcinoma in 74 (25, 7%), squamous cell carcinoma in 64 (22.7%) and NOS NSCLC in 40 (14%). Moreover, 4 patients had large cell carcinoma and 9 mesothelioma. Regarding NSCLC, 53% of patients were stage IV at diagnosis, 14% IIIB and 13% IIIA. 87% of those patients received first line chemotherapy, mostly with platinum–based doublets, while only 5% of adenocarcinomas showed EGFR mutations associated with TKI response and received targeted treatment. 30% of these patients also received second line chemotherapy. The remaining 39 patients were stage I or II at diagnosis. 15 were not eligible for surgery and only 24 underwent surgery.Conclusion: It seems that in Greece there is a high prevalence of SCLC, probably associated with the heavy history of smoking and most patients are diagnosed at a late stage. Policies for smoking cessation should be strengthened and a lung cancer screening program should be initiated.