RT Journal Article
SR Electronic
T1 Treatment of concomitant obstructive sleep apnea/hypopnea syndrome in patients with persistent poorly controlled bronchial asthma - Real opportunity to improve asthma control
JF European Respiratory Journal
JO Eur Respir J
FD European Respiratory Society
SP PA3584
DO 10.1183/13993003.congress-2015.PA3584
VO 46
IS suppl 59
A1 Iashyna, Liudmyla
A1 Feshchenko, Yurii
A1 Polianska, Maryna
A1 Ignatieva, Viktoria
A1 Zvol, Inna
A1 Moskalenko, Svitlana
A1 Kramarska, Natalia
A1 Opimakh, Svitlana
A1 Chumak, Iryna
A1 Diachenko, Natalia
A1 Nazarenko, Ksenia
YR 2015
UL http://erj.ersjournals.com/content/46/suppl_59/PA3584.abstract
AB Background: Common, but often poorly diagnosed and, consequently, not treated obstructive sleep apnea/hypopnea syndrome (OSAHS) in asthma patients - frequent cause of poor asthma control, in spite of adequate asthma therapy.Aims and objectives: to find out whether the addition of auto-CPAP therapy to the standard asthma treatment can improve asthma control.20 patients with persistent BA (FEV1 (68,0 ± 3,3)%, ACQ (1,7 ± 0,1) with first diagnosed and verified OSAHS (apnea-hypopnea index (AHI) – (33,6 ± 5,6)), 7 female and 13 male, in age (56,7 ± 2,2) years received auto-CPAP therapy in addition to their asthma therapy –one or two controllers according BA severity.Methods: General clinical examination, ACQ, Epworth Sleepiness Scale, quality of life questionnaire (SGRQ), pulmonary functional tests - PFT, polysomnography were assessed 1) at enrolment, 2) after 10 days of their usual asthma therapy (served as control) and 3) after course of CPAP treatment.Results: There were no clinically meaning and significant changes after 10 days of patient's usual treatment. After proper treatment of OSAHS by addition of auto-CPAP AHI decreased from (27,6 ± 4,6) to (6,6 ± 2,2)/hour, (p <0.05) vs control therapy.ACQ decreased from (1,7 ± 0,1) till (1,1 ± 0,1) (p <0.05), clinically meaning (>0,5 points). Clinically meaning (>4 points) and significantly (p <0.05) improved all domains of SGRQ. PFT data remained stable, within the reproducibility.Conclusion: use of auto-CPAP in in persistent partially controlled asthma patients with concomitant OSAHS allow improve asthma control.