TY - JOUR T1 - Prognostic factors in non-small cell lung cancer JF - European Respiratory Journal JO - Eur Respir J DO - 10.1183/13993003.congress-2015.PA4294 VL - 46 IS - suppl 59 SP - PA4294 AU - O. Neffati AU - L. Fekih AU - H. Kammoun AU - A. Ayari AU - I. Mejri AU - H. Smadhi AU - I. Akrout AU - H. Abdelghaffar AU - D. Greb AU - H. Hassene AU - M.L. Megdiche Y1 - 2015/09/01 UR - http://erj.ersjournals.com/content/46/suppl_59/PA4294.abstract N2 - Introduction : Lung cancer is one of the most frequently occurring neoplasms and usually has a poor prognosis because most of the patients present with advanced or metastatic disease at the time of diagnosis. Numerous prognostic factors (PF) have been studied.Aim: Study the prognostic factors in non small-cell lung cancer.Methods : A retrospective study had enrolled 269 cases of non small-lung cancer between January 2008 and December 2012.Results : The average age of ourpatients was61 years [44-80 years]. Lungcancer wasmore frequently observedin men (94,5%). Smoking wasnoted in 96% of patients. Histological types were adenocarcinoma (61%), squamous cell cancer (28%), non-smallcell carcinomacellsuntyped (11%) and large cell carcinoma (1%). TNM classification revealed stage IA (1,5%), IB (2%), IIA(3%), IIB (5%), IIIA (12%), IIIB (16%) and IV (60,5%). Median survival wasestimated at 575±70 days.Women , patients aged under 45 years and non-smoking patients have a better survival (p=0,005 ; 0,05 and 0,017 respectively). The other prognostic factors were the average intoxication tobacco, the stage of cancer, performance status, the number of metastases, the introduction of aspecific treatment, consultation delay and therapeutic delay (p=0,024; 0,031; 0,006; 0,001; 0,006; 0,46 and 0,001 respectively).Conclusion : Prognostic factors (PF) have a pivotal role in Clinical Oncology. They are helpful in the selection of treatment, provide insights into the disease process and the therapeutic response, and are fundamental in the design of clinical trials or in the interpretation of data from the literature. ER -