PT  - JOURNAL ARTICLE
AU  - Mariana Reimberg
AU  - Átila Alves dos Santos
AU  - Crislaine Santos
AU  - Beatriz Rodrigues Santos
AU  - Rejane Agnelo Silva de Castro
AU  - Matheus Elias Pacheco
AU  - Gustavo Falbo Wandalsen
AU  - Dirceu Solé
AU  - Simone Dal Corso
AU  - Fernanda De Cordoba Lanza
TI  - Functional capacity and peripheral muscle strength are reduced in asthmatic children and teenager
AID  - 10.1183/13993003.congress-2015.PA4826
DP  - 2015 Sep 01
TA  - European Respiratory Journal
PG  - PA4826
VI  - 46
IP  - suppl 59
4099  - http://erj.ersjournals.com/content/46/suppl_59/PA4826.short
4100  - http://erj.ersjournals.com/content/46/suppl_59/PA4826.full
SO  - Eur Respir J2015 Sep 01; 46
AB  - Introduction: A shuttle walk test (SWT) has been widely used for evaluating functional capacity and response to intervention in people with chronic lung diseases, but has never been used in pediatric asthmatic. Another possible systemic repercussion in this population is impaired skeletal muscle function, but studies investigating peripheral muscle strength (PMS) in these patients are scarce.Aim: To compare PMS and performance on a SWT between asthmatic children and teenagers and healthy volunteers.Method: 15 asthmatic participants (AG) (10years[8–11]) and 10 control participants (CG) (10years[12-15]) underwent spirometry, maximal isometric voluntary contraction for measuring quadriceps femoris (QF) and biceps brachii (BB) strength, and shuttle walk tests (SWT). Heart rate (HR) was continuously measured during the tests. Dyspnea and fatigue were recorded at the beginning and at the end of SWT.Results: Despite there being no difference in lung function between the AG (FEV1 104%[94–116], FVC 101%[91–109]) and CG (FEV1 104%[83–114], FVC 98%[80-105]), the AG walked shorter distances on the SWT (670m [544–746m]) compared to the CG (889m [593–1064m]) (p = 0.04).HR was similar between the AG and CG, as were dyspnea and fatigue. Compared to the CG, the AG showed reduced BB and QF strength (BB: 8.1kg[6.6–10.8kg] vs. 5.5kg[5.1-6.5kg], p = 0.02 and QF: 16.3kg[9.4–20.1kg] vs. 9.3kg[7.3–10.6kg], p = 0.01).Conclusion: Functional capacity is reduced in asthmatic children and adolescents. This is the first study to show impaired muscle function in this population and emphasizes the importance of including strength training as part of an exercise program. FAPESP 2014-12040-0; 2014/20857-6.